Rift Valley fever - Consequences of virus-host interactions

نویسندگان

  • Maria Baudin
  • Douglas Adams
چکیده

....................................................................................................... xiii Sammanfattning på svenska .......................................................................... xv Case report* .................................................................................................... 1 Part 1 – Infectious diseases and pregnancy ................................................................... 1 Part 2 – Rift Valley fever virus ........................................................................................ 1 Part 3 – Rift Valley fever disease .................................................................................... 2 Part 4 – Consequences of RVF ....................................................................................... 2 Part 5 – Diagnosis and treatment ................................................................................... 3 Part 1 – Infectious diseases and pregnancy ..................................................... 4 Viral infections affecting pregnancy ............................................................................... 4 Viral haemorrhagic fever .................................................................................................. 5 VHF during pregnancy ..................................................................................................... 6 Filoviridae ........................................................................................................................................ 6 Arenaviridae .................................................................................................................................... 7 Flaviviridae ...................................................................................................................................... 7 Bunyaviridae .................................................................................................................................... 7 Part 2 – Rift Valley fever virus ....................................................................... 10 RVFV virus structure, genome, and gene products .................................................. 10 L segment ...................................................................................................................................... 11 S segment ....................................................................................................................................... 11 M segment ..................................................................................................................................... 12 Virus-host-interactions ................................................................................................... 13 RVFV transmission ......................................................................................................... 15 Part 3 – Rift Valley fever disease ................................................................... 16 RVF in animals ................................................................................................................. 16

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Enemies and turncoats: bovine tuberculosis exposes pathogenic potential of Rift Valley fever virus in a common host, African buffalo (Syncerus caffer).

The ubiquity and importance of parasite co-infections in populations of free-living animals is beginning to be recognized, but few studies have demonstrated differential fitness effects of single infection versus co-infection in free-living populations. We investigated interactions between the emerging bacterial disease bovine tuberculosis (BTB) and the previously existing viral disease Rift Va...

متن کامل

Rift Valley fever virus: strategies for maintenance, survival and vertical transmission in mosquitoes.

Rift Valley fever virus (RVFV) is a mosquito-borne arbovirus causing severe disease in humans and ruminants. Spread of RVFV out of Africa has raised concerns that it could emerge in Europe or the USA. Virus persistence is dependent on successful infection of, replication in, and transmission to susceptible vertebrate and invertebrate hosts, modulated by virus-host and vector-virus interactions....

متن کامل

Multi-Faceted Proteomic Characterization of Host Protein Complement of Rift Valley Fever Virus Virions and Identification of Specific Heat Shock Proteins, Including HSP90, as Important Viral Host Factors

Rift Valley fever is a potentially fatal disease of humans and domestic animals caused by Rift Valley fever virus (RVFV). Infection with RVFV in ruminants can cause near 100% abortion rates and recent outbreaks in naïve human populations have suggested case fatality rates of greater than thirty percent. To elucidate the roles that host proteins play during RVFV infection, proteomic analysis of ...

متن کامل

Restriction of Rift Valley Fever Virus Virulence in Mosquito Cells

Arboviruses are maintained in a natural cycle that requires blood-sucking arthropod and vertebrate hosts. Arboviruses are believed to persistently infect their arthropod host without overt pathology and cause acute infection with viremia in their vertebrate host. We have focused on elucidating how a specific arbovirus, Rift Valley fever (RVF) virus, causes cytopathic effect in cells derived fro...

متن کامل

The Pathogenesis of Rift Valley Fever

Rift Valley fever (RVF) is an emerging zoonotic disease distributed in sub-Saharan African countries and the Arabian Peninsula. The disease is caused by the Rift Valley fever virus (RVFV) of the family Bunyaviridae and the genus Phlebovirus. The virus is transmitted by mosquitoes, and virus replication in domestic ruminant results in high rates of mortality and abortion. RVFV infection in human...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016